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What Are Bile Ducts? - Cleveland Clinic
Your bile ducts are the pipelines that bile travels through. The organs in your biliary system depend on your bile ducts to do their jobs.

Bile duct - Wikipedia
Bile is required for the digestion of food and is secreted by the liver into passages that carry bile toward the hepatic duct. It joins the cystic duct (carrying bile to and from the gallbladder) to form the common bile duct which then opens into the intestine.

Bile Duct Obstruction: Symptoms, Causes & Treatment
A bile duct obstruction occurs when a blockage or narrowing in your bile ducts prevents bile from flowing as it should. Gallstones are the most common cause.

Bile duct diseases Guide: Causes, Symptoms and Treatment Options
Bile ducts are drainage "pipes" that carry bile from the liver to the gallbladder and from the gallbladder to the small intestine. A variety of diseases can affect your bile ducts.

Everything To Know About Bile Duct Disorders: Signs, Symptoms, Causes ...
The bile ducts are small, tubular structures that play an important role in digestion by transporting bile -- a yellowish-green fluid -- from the liver and gallbladder to the small intestine.

Bile Duct Obstruction: Symptoms, Treatment, and Causes
A “duct” is a tube that carries specific bodily fluids. The bile ducts carry bile from the liver and gallbladder through the pancreas to the duodenum, which is a part of the small intestine.

Common bile duct - Wikipedia
The common bile duct (also bile duct) is a part of the biliary tract. [1][4] It is formed by the union of the common hepatic duct and cystic duct. It ends by uniting with the pancreatic duct to form the ampulla of Vater (hepatopancreatic ampulla).

Cholangiocarcinoma (bile duct cancer) - Symptoms and causes
Bile is made in the liver and flows into the gallbladder. It stays in the gallbladder until it's needed to help digest food. While eating, the gallbladder releases bile into the bile duct. The duct carries the bile to the upper part of the small intestine, called the duodenum, to help break down fat in food.

What are bile ducts? | Department of Surgery | Washington University in ...
Your bile ducts are small tubes that connect the organs of your digestive system. They connect the liver, gallbladder, and small intestines. Together, the bile ducts and these organs make up the biliary system. Bile ducts transport bile from the liver to the gallbladder and small intestine.

What Is Bile Duct? Functions, Disorders & Treatment
The bile duct carries bile produced by the liver to the small intestine, enabling the breakdown of fats and absorption of fat-soluble vitamins like A, D, E, and K.

* Hepatology101 LATEST NEWS *

                    *Filter: "Bile-Duct"

ERCP vs. Observation for Incidental Bile Duct Stones  NEJM Clinician
Molecular Test Doubles Detection of Bile Duct Cancer  University of Pittsburgh Medical Center
Bowel Disease, GLP-1s, and Colon Cancer; Herbs for MASLD? Managing Bile Duct Stones  MedPage Today
Perineural Invasion Linked to Poorer ICC Survival Outcomes  EMJ
Molecular Test Doubles Detection of Bile Duct Cancer  The ASCO Post
Addressing the Symptom Burden of Primary Biliary Cholangitis  Medscape Reference: Drugs, Diseases & Medical Procedures
Experts call to improve survival rates for bile duct cancer patients  Medical Xpress
Understanding remodelling of bile ducts to promote polycystic liver disease  Nature
Fractalkine and CX3CR1 are involved in the recruitment of intraepithelial lymphocytes of intrahepatic bile ducts†  Ovid
A Molecular Test Now Guiding Diagnosis and Transplant Decisions for Bile Duct Cancer Patients  University of Pittsburgh Medical Center
Development of a biodegradable prosthesis through tissue engineering, for the organ-replacement or substitution of the extrahepatic bile duct  www.elsevier.com
Role of Immune Cells in Biliary Repair  Frontiers
Bile Duct Repair in Human Liver Grafts: Effective Cholangiocyte Organoid Engraftment and Plasticity  Wiley Online Library
Aspirin Use May Help Prevent Bile Duct Cancer  Mayo Clinic News Network
Vanishing bile duct syndrome related to DILI and Hodgkin lymphoma overlap: A rare and severe case  www.elsevier.com

Common Hepatology Symptoms

Jaundice (Icterus) — Yellowing of the skin and sclera caused by elevated serum bilirubin levels due to impaired hepatic processing or biliary obstruction.

Ascites — Pathologic accumulation of fluid in the peritoneal cavity, commonly secondary to portal hypertension and advanced liver cirrhosis.

Hepatic Encephalopathy — Spectrum of neuropsychiatric abnormalities including confusion, asterixis, and altered consciousness resulting from neurotoxin accumulation.

Pruritus — Severe, generalized skin itching frequently associated with cholestatic liver diseases and systemic bile acid accumulation.

Right Upper Quadrant Abdominal Pain — Dull ache or sensation of fullness caused by stretching of Glisson's capsule surrounding an enlarged or inflamed liver.

Spider Angiomas and Palmar ErytHepa — Vascular cutaneous signs stemming from altered sex hormone metabolism and hyperdynamic circulation in chronic liver disease.

Dark Urine and Acholic Stools — Tea-colored urine from bilirubinuria paired with pale, clay-colored stools indicating impaired biliary drainage.

Milestones in Hepatology History

Discovery of the Australia Antigen (1965) — Baruch Blumberg identified the surface antigen of Hepatitis B, paving the way for diagnostic screening and the first HBV vaccine.

First Successful Human Liver Transplant (1967) — Dr. Thomas Starzl performed the world's first successful human liver transplantation at the University of Colorado Health Sciences Center.

Identification of Hepatitis Delta Virus (1977) — Mario Rizzetto discovered the delta antigen, characterizing HDV as a defective subviral pathogen reliant on HBV co-infection.

Cloning and Identification of Hepatitis C (1989) — Michael Houghton, Harvey Alter, and Charles Rice isolated the non-A, non-B hepatitis virus, officially naming it Hepatitis C.

Introduction of MELD Score System (2002) — The Model for End-Stage Liver Disease was adopted in the United States to prioritize liver allocation based on 3-month mortality risk.

Approval of Direct-Acting Antivirals for HCV (2013) — The FDA approved Sofosbuvir, ushering in an era of highly effective, interferon-free oral curative regimens for chronic Hepatitis C.

Nomenclature Shift to MASLD and MASH (2023) — Global liver societies renamed NAFLD/NASH to better reflect underlying metabolic pathology and eliminate stigmatizing language.

Current Hepatology Research

Bepirovirsen Functional Cure Trials — Evaluating antisense oligonucleotides to achieve a sustained loss of HBsAg and drug-free clinical response in patients living with chronic hepatitis B.

MASLD Diagnostics and Screening — Refining non-invasive biomarker panels and metabolic criteria to detect metabolic dysfunction-associated steatotic liver disease early in co-infected populations.

Hepatitis D Expanded Testing Protocols — Implementing reflexive antibody and RNA testing strategies to address global underdiagnosis of delta hepatitis co-infections.

Global Elimination Strategy Implementation — Tracking regional epidemiological data and public health interventions designed to accelerate viral hepatitis eradication goals.

RNA Interference (RNAi) Gene Silencing — Investigating small interfering RNA therapies to knock down viral transcripts and reduce antigen production in chronic liver infections.

MASH Fibrosis Biomarker Development — Validating novel serum panels and elastography metrics to monitor metabolic dysfunction-associated steatohepatitis regression without invasive biopsies.

In Vivo Gene Editing via Lipid Nanoparticles — Utilizing hepatic-targeted LNP delivery systems to correct monogenic metabolic liver disorders directly within host hepatocytes.

Gut Microbiome Alterations in Cirrhosis — Analyzing gut-liver axis dysbiosis to prevent bacterial translocation and manage portal hypertension complications in end-stage liver disease.